Under conventional IVF protocols, egg and sperm are combined in a dish, and fertilisation is allowed to take place organically. This leaves much to mechanisms beyond human control and requires a sizable number of motile sperm. ICSI, on the other hand, allows the embryologist to directly influence fertilisation, by injecting only a single, morphologically-sound and motile sperm into the retrieved egg, via tiny needle under microscope. It is a safe and proven method, regarded as the gold standard in overcoming male infertility.